Polymeric drug-delivery nanoparticles with surface-targeted ligands up to 1000 nm unlock targeted aqueous dosing.
The approach uses polymeric nanoparticles whose surfaces are chemically bonded to target molecules, forming particles (about 1–400 nm, up to 1000 nm) dispersed homogeneously in water. The technical significance is the ability to keep the formulation in the nano range for targeted binding while maintaining a stable aqueous dispersion without relying on bulky carriers. Previously, using this specific surface-targeted nanoparticle design for drug delivery likely required licensing from the patent holder.
Launch targeted injectable or topical drug-delivery products using surface-ligand polymeric nanoparticles dispersed in water.
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