AI & Infrastructure

Building the tools that build everything else

AI is the new electricity—but the infrastructure isn't ready. Model deployment is expensive. Fine-tuning is a dark art. Evaluation is broken. The picks-and-shovels opportunities in AI are as large as the applications themselves. We're looking for the platforms, tools, and infrastructure that will power the next decade of AI development.

What gets traction on Questd

  • Problems with a clear, specific victim — a job title, industry, or daily frustration
  • Moonshots that attract exceptional talent, or niche markets big enough to build on but overlooked by big players
  • Frustrations backed by real evidence — quotes, data, or personal experience
  • Problems where no good solution exists yet, only workarounds

Problems in AI & Infrastructure

32 problems

Academic research is being diluted by low-effort, repetitive publications.

·7w ago·@Reddit Community

The proliferation of formulaic, low-novelty academic papers, particularly in AI, is overwhelming valuable research and hindering genuine scientific progress. A solution is needed to identify and prioritize impactful contributions.

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Synthetic Humans: 100x Speed, 1% Cost

·140w ago·@Weekend Fund

Every decade, technology replaces a human-powered process with software. Postcards → texts. Blockbuster → Netflix. The next wave: synthetic humans—software that replicates human behavior with the scalability of bits. Deliver what only humans could do at 100x speed and 1% cost.

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Finally, Manageable Metadata

·15w ago·@Conviction

Manual metadata collection is painful and incomplete; legacy catalogs poorly support unstructured data. Build AI-driven classification, policy application, quality detection, and lineage understanding for modern data stacks.

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Loosening the Legacy Grip

·15w ago·@Conviction

Mainframe apps (COBOL, Assembler) are difficult to migrate due to language, complexity, tight coupling, and compliance risk. Use code generation to systematically extract logic, translate to modern languages, and generate documentation.

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Always Pick Up the Phone

·15w ago·@Conviction

Businesses miss approximately 50% of inbound calls, which is critical for lead generation. Build voice-based transactional systems handling qualification, reservations, appointments, and order tracking.

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AI Attention Mechanisms: A d^2 Dimensional Problem, Not n^2

·7w ago·@Reddit Community

A new mathematical proof suggests current AI attention mechanisms are fundamentally d^2-dimensional, not n^2, potentially unlocking significant efficiency gains and enabling more stable, faster AI model training and inference.

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The AI Chief of Staff

·11w ago·@Y Combinator

CEOs have chiefs of staff. Everyone else has overflowing inboxes and chaotic calendars. Build the AI assistant that actually handles your email, schedules your meetings, and executes your tasks—without creating more work than it saves.

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The AI-Native Salesforce

·10w ago·@Y Combinator

Salesforce and ServiceNow were founded 25 years ago and rode cloud to $200B+ market caps. AI presents the same once-in-a-generation platform shift. Build the enterprise software where AI isn't a feature—it's the foundation. Think Cursor for sales, HR, and finance.

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The All-Seeing Eye

·15w ago·@Conviction

Millions of deployed cameras lack rich indexing and semantic understanding. Build full-stack security services using on-device models for sophisticated computer vision analysis.

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Securing the Software Supply Chain from Compromised Developer Tools

·7w ago·@Reddit Community

Developer tools, like Trivy's VSCode extension, are increasingly targeted, posing a significant risk to the software supply chain. A robust solution is needed to ensure the integrity of these critical components.

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The Enterprization of AI: Build the Missing Infrastructure Layer

·146w ago·@Weekend Fund

ChatGPT reached 100M users in two months. Enterprise adoption is crawling. Why? Enterprises lack the privacy, security, compliance, data integration, and governance tooling required to deploy AI responsibly. Build the infrastructure that unlocks AI for the Fortune 500.

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The OfficeVerse: AI Agent Training Environments

·15w ago·@Conviction

Agents trained on games and simulations lack real-world enterprise complexity. Build multi-agent simulations reflecting actual office communication (Slack, video calls, file sharing) for training domain-generalist work agents.

10
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Replace $100B in Government Consulting with AI

·10w ago·@Y Combinator

The federal government spends $100B+ annually on consultants from Deloitte, Accenture, and Booz Allen. Most of this work—research, analysis, report writing, process documentation—can now be done by AI. Build software that makes consultants obsolete.

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AI Tools for Government at Scale

·9w ago·@Y Combinator

Government processes millions of forms annually but still prints digital submissions for manual review. AI can process applications, detect fraud, and clear backlogs—if you can navigate the sales cycle. Once you're in, you're in for decades.

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Automate Enterprise Back-Office Processes

·69w ago·@Pathlight Ventures

Build AI-powered automation for enterprise back-office processes—finance, HR, procurement—that still rely heavily on manual work.

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Automated Root Cause Analysis

·15w ago·@Conviction

On-call engineers spend hours debugging without systematic incident analysis. Build lightweight agents that access logs and metrics to retrieve context and suggest fixes based on runbooks and prior incidents.

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Autonomous HR (and IT) Helpdesk

·15w ago·@Conviction

Large HR teams handle high-volume repetitive events like hiring, exits, and role changes with manual processing. Build conversational search interfacing with HRIS systems for access-controlled answers and automated record updates.

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Build AI Software That Captures the $22-117T Productivity Opportunity

·64w ago·@ARK Invest

AI software could boost global productivity by $22-117 trillion by 2030. OpenAI is projected to surpass $10B revenue in 2025. Build the next wave of AI productivity tools.

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Build AI-Managed Advertising Platforms

·64w ago·@ARK Invest

AI-managed ads are expected to capture 54% of the $1.1 trillion digital ad market by 2030. That's $594B in AI-mediated advertising spend.

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Infrastructure for Multi-Agent AI Systems

·10w ago·@Y Combinator

AI agents are evolving from single chatbots into distributed systems with thousands of sub-agents running in parallel. This is the Hadoop/Spark moment for AI. Build the infrastructure that makes orchestrating agent fleets as routine as deploying a web service.

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IT Can't Fix What IT Can't See

·15w ago·@Conviction

50% of CMDB data is unreliable, contributing to over 60% of IT incidents caused by misconfigurations. Build agentless discovery, graph construction, and AI reasoning for robust enterprise IT visibility.

20
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Commercial-Grade AI Security for Every Home

·12w ago·@Y Combinator

The $20B home security market is stuck on motion sensors and grainy cameras. Commercial buildings have AI that distinguishes threats from false alarms. Bring that intelligence to every home—security that recognizes faces, detects anomalies, and actually protects.

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Comply or Die: Build the Regulatory Infrastructure for Tech's Next Era

·149w ago·@Weekend Fund

Tech is under regulatory siege from every direction—AI licensing, teen safety laws, crypto enforcement, hardware restrictions. Every new regulation creates mandatory adoption of compliance tools. Build the infrastructure that helps companies survive the regulatory onslaught.

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Cursor for Product Managers

·9w ago·@Y Combinator

As AI coding agents handle implementation, the bottleneck shifts to deciding what to build. Create the intelligent product management tool that analyzes customer data, proposes features, and generates specs that coding agents can execute.

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Enable SMB Security Through Managed Service Providers

·69w ago·@Pathlight Ventures

Build security tools designed for MSPs to deploy and manage across their SMB client portfolios.

6
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Enterprise Vibe Coding

·15w ago·@Conviction

Consumer no-code tools lack enterprise features like access control, integrations, and compliance. Build an enterprise-specific application builder with business-oriented templates and security features.

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Generative Video as a Computing Primitive

·10w ago·@Y Combinator

Video generation models now produce photorealistic 8-second clips indistinguishable from reality. Soon, generating video will cost nearly nothing. Treat video as a new computing primitive—not output—and build apps, tools, and infrastructure for this unlimited-video world.

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Next-Gen Autocomplete

·15w ago·@Conviction

There's no Copilot-like experience for general computing (email, browsing, authoring). Build a browser extension that learns personal writing style, handles multimodal input (screenshots, voice), and provides second-brain functionality.

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Reasoning Infrastructure for Companies

·15w ago·@Conviction

Large enterprises lack unified reasoning systems and integration hubs for AI actions. Build a live enterprise ontology mapping plus centralized action registry for AI execution across legacy systems.

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Reinvent the Phone Call with Voice AI

·11w ago·@Y Combinator

Phone calls are a $100B+ market that hasn't fundamentally changed in a century. Voice AI can now hold real conversations—scheduling, selling, supporting—with latency and quality indistinguishable from humans. Build the future of voice.

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Use the Recipe: AI Application Framework

·15w ago·@Conviction

AGI is increasingly an operational challenge of bringing tasks under distribution. Build AI applications that scale complex work across domains using reasoning models and tool access.

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Web Data APIs

·15w ago·@Conviction

AI models need live data access but existing APIs lack page content, outlinks, and edit history. Bootstrap comprehensive, vertically-focused web indexes with parsed content and real-time updates.

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Explore Other Categories

Moonshots

The problems that define the next century

Some problems are so large that solving them changes everything. Fusion energy. Brain-computer interfaces. Reversing aging. These aren't incremental improvements—they're civilizational shifts. We're looking for the technical breakthroughs and bold bets that seem impossible until they're inevitable.

Niche Markets

Small markets that desperately need a champion

The best businesses often start in markets that look too small. Vertical SaaS for dry cleaners. Tools for independent truckers. Software for yacht brokers. These niches are ignored by big companies but represent real pain for real people. Dominate a niche, then expand.

Future of Work

Reinventing how 4 billion people spend their days

Work is being rebuilt from scratch. Remote collaboration. AI-augmented productivity. The death of the 9-to-5. The rise of the portfolio career. The companies that define how we work in 2035 are being built now. We're looking for the tools, platforms, and systems that will shape the next era of human productivity.

Creator Economy

Powering the next generation of independent creators

50 million people now consider themselves creators. Most make less than $500/year. The infrastructure is broken—discovery is algorithmic roulette, monetization favors platforms over people, and burnout is the norm. We need better tools for creators to build sustainable businesses around their work.

Longevity

Adding decades to the human healthspan

The science of aging is accelerating. Senolytics. Gene therapy. Epigenetic reprogramming. For the first time, extending healthy human lifespan is a serious engineering challenge, not science fiction. The companies solving these problems won't just build billion-dollar businesses—they'll change what it means to be human.

Rebuild Money

Fixing the infrastructure of global finance

Financial infrastructure was built for a different era. Cross-border payments take days. 2 billion people are unbanked. Small businesses can't access capital. Crypto promised a revolution but mostly delivered speculation. We're looking for practical solutions that make money work better for everyone.